Biochemistry for people in a hurry In 1964, THC (tetrahydrocannabinol) was identified as the psychoactive chemical in marijuana responsible for making users “high.”1,2 Nearly thirty years later, in trying to figure out how it made the user high, the Endocannabinoid System (ECS) was discovered.3,4 Although its founding and name are derived from the cannabinoid THC, […]